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Duphalac for children: instructions for use. Dufalac - instructions for use for adults and children Laxative for children duphalac instructions

The gastrointestinal tract is underdeveloped in children. In addition, failures in the excretory system often occur as a result of a violation of the microflora. Therefore, constipation in a child is a common problem that requires the right solution. In pediatrics, laxatives are prescribed with great care and under medical supervision. There are not many medicines for constipation for children. One of them is "Duphalac" (syrup). Instructions for use, consumer reviews, the cost of the drug are described in this article.

Active components of the drug "Duphalac"

The medical preparation "Duphalac" consists of lactulose and purified water. This composition of the drug has a high level of safety for use in pediatric practice. Since the active substance is practically not absorbed into the bloodstream, but has a local effect in the intestines, after which it is excreted from the body naturally. Therefore, Duphalac is used for newborns, as well as for the treatment of pregnant women.

Release form

Syrup "Duphalac" is available in two forms:

in disposable sachets of 15 ml;
in plastic bottles of 200 ml, 500 ml or 1 liter.

Depending on the age of the small patient and the course of treatment recommended by the doctor, the most convenient form of packaging is selected. So, for kids under 7 years old, it is more practical and economical to choose bottles of various sizes. "Duphalac" for a child older than the specified age is best purchased in one-time sachets that already have the volume of syrup recommended for this age, namely 15 ml.

The essence of the action of the drug

How does simple lactulose help to cope with such a delicate matter as constipation? The principle of operation is that as a result of metabolic processes, the active substance tends to break down to organic acids. They, in turn, affect intestinal motility. And also due to fluid retention under the influence of ongoing oxidative processes, the consistency of feces softens and their volume increases. Thus, "Duphalac" for a child gently, without damaging the intestinal walls, activates the process of natural bowel movement.

In addition to the fact that the drug does not have an aggressive effect and has a high level of safety, the lactulose contained in the preparation contributes to the formation of flora useful for the normal functioning of the intestine in the form of lacto- and bifidobacteria. How does this happen? In the human body, there are normally important microorganisms that perform various functions. When any digestive disorders occur, most of them die, and pathogenic microflora begins to grow, which leads to various health problems, including constipation. Under the influence of metabolic processes that occur in the intestine after taking the drug, a favorable environment is formed for the growth of beneficial bacteria. Increasing in quantity, they help fight the problem of constipation. Thus, the laxative "Duphalac" gently and naturally corrects the flora and starts the normal physiological intestinal motility.

Analyzing the principle of operation of this medicinal product, it can be noted that compared to medicines, the purpose of which is only mechanical irritation of the intestine to activate the defecation process (for example, various suppositories and microclysters) and have a one-time effect, the Dufalac laxative is designed to fully restore the physiological functions of the intestine, which will have a long-term result. But, on the other hand, this drug is not intended for a "momentary" solution to the problem. Its action can begin 2-3 days after the first dose.

Indications for the appointment of syrup

Has some indications of "Duphalac" (syrup). Instructions for use indicate the following:

First of all, the doctor will recommend this medication for constipation (lack of defecation) in order to restore the physiological process.
Sometimes the drug is prescribed before surgical operation or after it, when softening of feces is required.
The drug is also used to treat liver encephalopathy.

At what age can you give a child "Duphalac"?

The drug "Duphalac" for a child, if indicated, can be prescribed by a doctor even for the treatment of a baby in the first year of life. This choice is explained by the fact that the active substance of the drug is absorbed into the bloodstream only in small doses. Lactulose acts only locally and does not affect the functioning of other systems and organs.

Nevertheless, any laxatives, including Duphalac for newborns, are used only in the most necessary cases, since such drugs can be addictive. This means that a laxative with an incorrectly chosen regimen of administration can lead to a complete stop of intestinal motility and dependence on the drug. Therefore, it is very important to correctly calculate the dosage of the syrup and the duration of the course.

Dosage for children

So how much to give? "Duphalac" is prescribed to the child in a dosed manner. It depends on the age and complexity of the disease. Correctly determine the dosage of the drug for children can only be a pediatrician. The instructions for the syrup indicate the following indicators:

For children up to a year, the daily dose is up to 5 ml. It can be divided into several methods. How to give "Duphalac" crumbs up to a year? Before using the syrup for babies of this age, it should be diluted in juice, milk or food. Since the syrup has a thick, viscous consistency without a pronounced odor, children may refuse to take the drug or an involuntary gag reflex may occur. In this case, the drug will not only not bring the expected benefit, but can also cause prolonged vomiting, which can only be stopped with special drugs.
Children under 6 years of age can take up to 10 ml per day, also dividing the dose into 2-3 doses.
For children 7-14 years old, it is convenient to use one-time sachets of the drug, with a volume of 15 ml.

The drug bottle contains a measuring cap, with which it is convenient to measure "Duphalac" for a child. Thanks to such a simple device, the possibility of error in measuring the dose of the drug is significantly reduced, so it is not difficult to use the drug at home.

Possible adverse reactions

The syrup is usually well tolerated by children without causing side effects. But in rare cases, such reactions are noted:

flatulence;
nausea;
vomit;
stomach ache;
diarrhea;
in case of an overdose or a long course of administration, an electrolyte imbalance may occur.

Most often, after stopping the drug, these symptoms disappear on their own and do not require medical treatment. If any adverse reactions to Dufalac are noticed, its further use should be postponed and a doctor should be consulted about the advisability of choosing another drug.

Contraindications for use

Has some contraindications "Duphalac" for a child. Namely, you can not use this drug in the following conditions:

intestinal obstruction;
risk of intestinal rupture or bleeding;
individual intolerance to the active substance - lactulose.

Syrup "Duphalac": application, price

The price of syrup depends on the volume of packaging. So, a bag consisting of a single dose of 15 ml will cost about 50 rubles. A bottle of 200 ml costs about 600 rubles, 500 liters - 900 rubles.

Lack of movement, fiber in the diet and clean drinking water lead to dysfunction gastrointestinal tract, which leads to the appearance of an unpleasant problem - constipation. And if it does not go away for a long time, there is a need for the use of drugs.

Today, pharmacies are full of a variety of laxatives in the form of tablets, suspensions, syrups and powders. And, based on the characteristics of your body and the degree of manifestation of the disease, it is easy to choose the right drug. Figuratively, all laxatives can be divided into fast-acting and laxatives with a gradual "soft" effect. One of these drugs is Dufalac, which has already managed to prove itself.

For ease of use, Dufalac has two forms of release: suspension (powder) and syrup, sweet in taste (for convenience, a measuring cup is attached). Suspension is less common. It is released from pharmacies without a prescription.

The drug with a mild laxative effect basically contains the substance lactulose, which among doctors is considered harmless and finds its use in adults, infants, pregnant and lactating women. Lactulose is the whey that remains after cheese is made.

The substance enters the stomach in its original and unchanged form and begins to act there, additionally helping our body to produce more bifidobacteria and lactobacilli, which favorably affects the restoration of the natural intestinal microflora. A healthy microflora plays a crucial role in regular emptying, which should occur without the use of special preparations.

How the action happens

Entering the intestine, the drug increases the osmotic pressure. The content in the intestine becomes larger, which affects the consistency, and also increases peristalsis. In the large intestine, the concentration of water changes, the "knocked down" feces are additionally softened and, as a result, emptying occurs gently and painlessly. The physiological rhythm is restored and constipation disappears.

Instructions for use, attached to any form of release of the drug, contains complete information about it:

It is necessary to prescribe the drug strictly according to indications, taking into account contraindications.

Application

A big plus of the drug is the lack of restrictions on the timing of use. It can be used, if necessary, both once, and the entire necessary treatment period.

For the elderly, the expediency of taking the medicine is due to the appearance of chronic or very frequent constipation. The disease occurs due to a decrease in blood supply in the small pelvis, weakening of the muscles of the anterior abdominal wall and weakness of the muscles of the pelvic floor. The drug is generally well tolerated by the elderly and does not worsen their blood biochemical parameters. The dosage for the patient is selected individually.

For children, the medicine is prescribed by the district pediatrician, taking into account the age, stage of treatment and the absence of allergies to the main active ingredient.

The child can tolerate the drug from 6 weeks of age. However, taking Dufalac is strictly prohibited in case of suspected appendicitis, intestinal obstruction or intestinal bleeding.

Indications for use

From constipation and its prevention for medical purposes, it is prescribed in the presence of operations on the colon, hemorrhoids. Widely applicable in the treatment of hepatic coma.

Dufalac should not be used in cases of:

special metabolic disorder (galactosemia);
with intestinal obstruction;
intolerance to the components of the drug.

The medicine contains a minimum amount of sugars, which makes it possible to use it in people with diabetes, subject to strict doses recommended by the doctor.

Mode of application

To achieve the maximum effect, the drug is recommended to be used correctly: at the same time of day.

Morning is the best time to take. When food enters an empty stomach (ideally, a glass of clean, drinkable water should be drunk before breakfast), the secretion of a special gastric hormone gastrin begins and peristaltic waves are launched. Entering the stomach with food, the drug is easier to get into the large intestine. The suspension should be swallowed quickly, without delaying in the oral cavity.

For the onset of the desired laxative effect, it is necessary to normalize the water-drinking balance. Softening stools and gentle bowel movements involves using fluid from the body's water reserve. Therefore, during the use of Dufalac, it is worth drinking more.

In some cases, the drug is prescribed in the form of enemas in a ratio of 300:700 (syrup: water).

Dosage

The dose for admission is prescribed in the instructions and is selected by the doctor individually. It happens primary and subsequent. It is rational to start taking it after consulting a doctor.

The initial volume of the drug is usually 15-45 ml, supporting - in the amount of 10-25 ml. There are times when one morning dose is not enough, and to improve the effect, it is recommended to take the medicine in the evening. Increasing the dose over several days may lead to unwanted side effects.

The first day of admission, as a rule, will not give the desired laxative effect. The drug begins to act two days after the start of use.

In the treatment of hepatic encephalopathy, the drug is prescribed as a powder of 20-30 g or 30-50 ml of syrup 3 times a day. The use of Duphalac in hepatic coma helps to improve the mental state of patients, reduce the severity of the disease and reduce the level of ammonium ion concentration in the blood.

Side effects:

Flatulence is the most common undesirable effect in the first days of taking Duphalac. Usually disappears soon.
Abdominal pain is less common.
Nausea and vomiting are extremely rare.

All this can lead to electrolyte imbalance in the body, which is a consequence of the loss of a significant amount of fluid. This condition is dangerous, as the heart rhythm, muscle contractions and brain function are disturbed.

At the first manifestations, you should compensate for the lack of water, stop taking the drug and consult with a specialist on the advisability of its further use.

Analogues

As analogues of Dufalac, pharmacies also offer drugs based on lactulose:

kids powder;
Laktulak;
Lactulose;
Silact.

Duphalac is a laxative drug that has become widespread due to its mild effect combined with effectiveness.

This product is made in the Netherlands. The active substance affects the condition of the intestinal walls, helps to cope with constipation.

On this page you will find all the information about Duphalac: full instructions for use for this drug, average prices in pharmacies, complete and incomplete analogues of the drug, as well as reviews of people who have already used Duphalac. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Laxative.

Terms of dispensing from pharmacies

Released without a prescription.

Prices

How much is Dufalac syrup? The average price in pharmacies is at the level of 300 rubles.

Release form and composition

"Duphalac" is available in the form of a viscous syrup, colorless or light yellow.

The main active ingredient is lactulose, its content in 100 ml of syrup is 66.7 g. The auxiliary component of the drug is purified water.

The syrup comes in bottles of 200, 500 ml, there are even liter ones. Additionally, for convenience, the container is supplied with a measuring cup. Another possible form of release is disposable sachets of 15 grams, ten pieces per pack.

Pharmacological effect

Dufalac has a hyperosmotic laxative effect, enhances intestinal motility, improves the absorption of calcium and phosphate salts, and also helps to eliminate ammonium ions from the body.

The intestinal flora of the colon breaks down lactulose into organic acids, which lower the pH and increase the osmotic pressure. As a result, the volume of intestinal contents increases, which stimulates peristalsis and affects the consistency of the stool. According to reviews, Dufalac effectively helps to get rid of constipation and restore the physiological rhythm of bowel movements.

As a prebiotic, lactulose stimulates the growth of beneficial bacteria, in particular lactobacilli and bifidobacteria, while the growth of potentially harmful bacteria such as Escherichia coli and Clostridium spp., on the contrary, is inhibited. As a result, this provides a more favorable balance of intestinal microflora.

Indications for use

The main one on the list is severe chronic constipation. Also, the drug is used to soften the stool for medical purposes or before surgery on the colon or anus.

In addition to these main indications, there are several other factors that require the use of Duphalac:

prophylactic treatment for hepatic encephalopathy, coma or precoma;
pain syndrome resulting from the removal of hemorrhoidal cones;
or enteritis in cases of occurrence;
putrefactive dyspepsia syndrome in acute food poisoning in a child;
colitis and colon polyps.

Contraindications

Do not take Duphalac if:

galactosemia;
colostomy and ileostomy;
intestinal obstruction for various reasons;
suspected acute appendicitis;
increased individual sensitivity to the components of the drug;
hereditary or acquired intolerance to active substances;
rectal bleeding of non-hemorrhoidal origin;
diabetes mellitus (this item is not a direct ban on the use of the drug, but before use, you need to consult a doctor).

Use during pregnancy and lactation

Lactulose is a safe component for women during the period of expectation of a child and breastfeeding, so Dufalac is indicated if necessary. The use of the drug by the mother does not affect the condition of the fetus or newborn, but the dosage and regularity of administration must be agreed with the attending physician.

Instructions for use

The instructions for use indicate that the doses of Duphalac in the treatment of constipation and for softening stools for medical purposes are presented in the table.

As a rule, the dose can be reduced after 2 days of administration, depending on the needs of the patient.

The drug is recommended to be taken 1 time per day during meals. The clinical effect occurs after 1-2 days (this is characteristic of the action of lactulose). The dose or frequency of administration is increased if there is no improvement in the patient's condition within 2 days of taking the drug.

In the treatment of hepatic coma and precoma, the initial dose is 30-45 ml of syrup.

In acute cases, Duphalac can be administered as an enema in a ratio of 300 ml of Duphalac syrup and 700 ml of water.

How long does it take for Duphalac to work?

The manifestation of the therapeutic effect directly depends on the use of a certain dosage and the disease against which the therapy is being carried out. In addition, Duphalac is characterized by a mild effect, so it cannot be called very fast.

The desired result appears 4-12 hours after administration. When answering the question of how quickly Duphalac acts, there are cases when you have to wait even about a day. In a child, metabolic processes proceed much faster, so the effect of Dufalac in them manifests itself after a couple of hours.

Side effects

The use of Duphalac in the first days of treatment can provoke flatulence (increased flatulence). This symptom disappears on its own after a few days.

Possible appearance side effects from the side nervous system: rarely - convulsions, headache, dizziness. In rare cases, allergic reactions are noted; arrhythmia, myalgia, fatigue, weakness.

Overdose

When taking high doses of the drug, diarrhea and abdominal pain are possible. Cancellation of the drug or a decrease in its dose eliminates these manifestations. In case of violation of the electrolyte balance, correction is required by the introduction of electrolyte solutions.

special instructions

If there is no effect from taking the drug for several days, you should consult your doctor.

It should not be used for abdominal pain, nausea, vomiting without verification of the diagnosis.
Use with caution in patients with diabetes mellitus, especially in inflammatory lesions of the colon.
With long-term treatment (more than 6 months), the level of potassium, chlorine and carbon dioxide in the blood plasma should be regularly monitored.
Patients with intolerance to galactose, fructose should not use this drug. Duphalac for newborns can only be used under medical supervision.
Use with caution in patients with gastrocardiac syndrome. In such cases, treatment should be started at low doses and increased gradually to avoid flatulence.

If diarrhea occurs, lactulose should be discontinued.

drug interaction

With simultaneous use with broad-spectrum antibiotics, it is possible to reduce the therapeutic efficacy of lactulose.

With the simultaneous use of lactulose, it can disrupt the release of active substances from enteric preparations with pH-dependent release due to the fact that it lowers the pH of the intestinal contents.

Many mothers often do not know how to overcome the problem of constipation in a small child. In search highly effective means they overpay a lot of money, but never see the expected result. So, if you are also in this situation, pay attention to the unique syrup - Duphalac. This laxative has a mild effect, and a unique formula based on lactulose allows you to eliminate various forms of constipation in the most difficult diseases.

Due to its gentle effect on the intestinal wall, it can be used even for newborns and older children. hallmark The drug is non-addictive and a quick solution to the problem of constipation. The laxative will be relevant for food poisoning, dysbacteriosis, and other difficulties with the gastrointestinal tract.

The drug is often attributed many pediatricians, as it works very gently, facilitating the movement and cleansing of the body from stagnant feces in children different ages. In addition, he can handle a variety of forms of constipation, violations of the composition of the intestinal microflora, etc.

Features of the drug

Duphalac's active ingredient is lactulose. This simple carbohydrate, a disaccharide, does not remain in the body and is not absorbed by the walls of the stomach and intestines. As well as a laxative, it does not affect the mucous membrane, which can be called its indisputable advantage, which allows the use of the medicine even for newborns.

Of the features of the drug, it is important to highlight the following:

Duphalac is available for sale in the form of a syrup, which is characterized by a sweetish aftertaste and a yellowish tinge. Any flavoring substances, artificial colors and other similar elements are absent;
100 ml of a viscous liquid contains purified water and lactulose;
the composition is packaged in small bottles of 200, 500 and 1000 ml;
to simplify use, the manufacturer supplies the drug with a measuring cup.

It is important to note that in pharmacies you can find separate single use sachets. Each of them contains 15 ml of laxative syrup. There are 10 bags in the package.

As for the pharmacological action, it consists in such features:

the drug promotes the rapid development of new lactobacilli in the colon;
it is a good stimulation of intestinal motility;
causes rapid softening of feces;
promotes faster absorption of phosphates, calcium salts and other substances;
quickly and effectively removes ammonium ions from the body.

A noticeable result from the use of Dufalac is noticed in a day.

The benefits of the drug

Many buyers and pediatricians find the drug very effective, so its popularity is growing rapidly. A lot of positive feedback is due to the following reasons:

Indications and contraindications

Laxative syrup will be indispensable in the following cases:

if the child suffers from dysbacteriosis;
functional constipation;
acute food poisoning;
hepatic encephalopathy;
anal fissure.

It can also be used to soften feces chronic form hemorrhoids, enteritis, during bacterial carriage, and complete cleansing of the body, in particular, the intestinal walls, before the upcoming diagnostic examination.

In some cases, the drug is completely contraindicated and prohibited for use. Sometimes, when taking it, you need to be careful, take into account the correct dosage and recommendations of doctors.

Before you buy medicine at the nearest pharmacy, be sure to visit a pediatric gastroenterologist, describing your problem in detail. Only after careful laboratory research, diagnosing a patient in a clinical setting and other similar work, the doctor can determine the appropriate dose of a laxative based on lactulose. It is possible that he will prescribe another drug.

As for the restrictions when Duphalac is completely contraindicated then they include:

galactosemia;
acute intestinal obstruction;
excessive sensitivity and individual intolerance to individual components of the drug;
diabetes;
intestinal bleeding of unknown etiology;
individual lactose intolerance;
hepatic encephalopathy.

General application rules

In most cases, the doctor determines the exact dosage for a specific situation and age category, taking into account the individual characteristics of the child, as well as the type of disease. For children, the drug is taken exclusively inside.

With regard to the general rules of application, which characteristic of all cases, then they look like this:

Instructions for use for newborns

A problem such as constipation in a child can become cause unbearable pain in the abdomen, as a result of which, the baby will stop eating and sleeping. He will constantly cry and scream, giving himself and his parents a lot of additional difficulties.

Fortunately, Dufalac laxative syrup can be used to combat this problem. It is indispensable in the early stages of life, provided that a neonatologist and a pediatric gastroenterologist have carried out a full examination and approved such a medicine. Experienced pediatricians highlight the particular effectiveness of the remedy in the treatment of constipation and dysbacteriosis in the smallest crumbs. If the frequency of administration and dosage are chosen correctly, side effects will practically not appear.

Newborn babies can be given a laxative in two forms:

together with breast milk or water;
in undiluted form.

How exactly to use the medicine, the doctor decides, given the condition of the small patient.

It is best to give the baby Duphalac after a night's sleep or during morning feeding.

Concerning correct dosage, then it is defined by such subtleties:

if we are talking about the fight against constipation, then the first 3-4 times you can give 1 ml of the drug. You need to fight dysbacteriosis 1.5 ml;
if the problem of constipation continues to progress, the volume of syrup used should be increased to 5 ml. A complete therapy of dysbacteriosis is accompanied by the use of 3 ml of Duphalac.

Experienced doctors do not recommend using the daily dose in the first days of prevention or treatment of dysbacteriosis and constipation. In most cases, this leads to increased gas formation, which causes the drug. It is better to start with small doses of 1-1.5 ml.

Being engaged in treatment, the drug should be given systemically, without missing days. It is important to monitor the condition of the baby, increasing the dosage in the absence of a noticeable result. You also need to show the baby to the doctor - perhaps he will prescribe another drug.

It is important to review the diet of a nursing mother. Very often, due to malnutrition, there are problems with stools in babies. If constipation has become persistent, doctors advise replacing breast milk with special mixtures that restore normal bowel cleansing.

The effect of a laxative syrup based on lactulose is noticed a few hours after ingestion. Sometimes, you need to wait a day, or even two.

In the future, intestinal motility improves significantly, and the composition of the microflora normalizes.

If you decide to treat constipation and dysbacteriosis in a small baby, do not forget about special gymnastics, including abdominal massage. Try to stroke your tummy slowly. clockwise hand movements without pressing the tummy too hard. What exercises to use for your child, you can find out at the appointment with the neonatologist. In any case, it is important to follow all the recommendations and follow the basic rules of the treatment course. As a result, efficiency will be maximum.

How to take the remedy for children from one year and older

Older kids require a different dosage for constipation. The daily rate is determined by such subtleties:

from the age of one year to six years, it is enough to use 5-10 ml;
if we are talking about the treatment of 7-14-year-old children, the optimal dosage is 10-15 ml.

If you intend to restore the normal intestinal microflora of your child, then be guided by the following features:

children from one to three years old need no more than 3 ml medical syrup;
at the age of 4 to 6 years, 5 ml of the substance is enough;
if the baby is 7 years old, the optimal dosage is increased to 10 ml.

To normalize the number of beneficial bacteria in the intestines, it is better to use the remedy in the morning and lunch. For older children, the dose should be increased, otherwise it may cause flatulence.

It is important to note that Dufalac is considered a highly effective drug that has excellent laxative effect for small patients. It is important to monitor the outcome of therapy. If constipation continues to torment the baby for several days, it is better to immediately go for a consultation with a doctor. Very often, these symptoms appear with more serious problems, including disruption of the digestive tract and a number of chronic diseases.

Side effects in overdose

If you do not follow the prescribed dosage, this can lead to several side effects and negative phenomena. Among them: pain in the abdomen, diarrhea, flatulence, electrolyte imbalance with frequent bowel movements.

To solve the problem, it is enough to reduce the dosage, stop taking the laxative and talk to the therapist.

If you follow the basic recommendations for taking the drug at home, you will be able to avoid many side effects. It is also necessary to follow the correct dosage recommended by the doctor. It is important to use Duphalac under the direct supervision of a pediatric gastroenterologist and neonatologist. If necessary, the specialist will change the daily dose or change the course of treatment to include other drugs.

If you are in doubt about whether to buy a product to treat your baby, read the reviews of other parents and consult a doctor. Most likely, the drug will be the best solution for solving problems such as childhood constipation and diarrhea.

Treatment of constipation is a delicate problem, which is not in a hurry to tell friends and doctors. There are drugs that can be used without a doctor's prescription for episodic and chronic defecation disorders. Duphalac, when taken orally, has a laxative effect and improves the composition of the intestinal microbiota.

When lactulose is dissolved in water, the laxative Duphalac is obtained. The active ingredient was created as a result of synthesis from the residues of galactose and fructose (milk and fruit sugar). By chemical structure is a disaccharide. Lactulose has no natural analogues. The raw material for the production of medicines is whey processing products.

Duphalac for children in terms of lactulose concentration does not differ from that for adults. You can give your child a syrup that contains plum flavor.

100 ml syrup contains 66.7 g of lactulose. The volume of Duphalac bottles: 200, 500, 1000 ml. They also produce sachets that contain 15 ml of syrup (a dose for an adult and a teenager). The number of sachets in one carton - 15 pcs. The drug is produced in Russia and the Netherlands.

Pharmacological properties and pharmacokinetics

The laxative effect of Duphalac is due to the properties of disaccharide molecules. Lactulose after taking the syrup helps to soften the processed food masses inside the colon. The content moves more easily to the anal canal.

Lactulose, in addition to a laxative, has other pharmacological properties:

creates suitable conditions for lactobacilli and bifidobacteria as part of the microflora;
suppresses pathogenic strains of salmonella and rotavirus;
restores the natural rhythm of defecation;
helps to remove toxins.

The breakdown of lactulose occurs under the influence of the microflora of the colon. Thanks to the work of bacteria, disaccharides and monosaccharides break down, low molecular weight acids and other substances are released. The pH decreases and the osmotic pressure increases. The volume of digested food in the lumen of the colon increases, peristalsis becomes more active. The chair is liquefied, the constipation passes.

Duphalac does not reduce the absorption of vitamins, but increases the intake of important mineral components from the intestines. Lactulose protects the intestinal walls and systemic circulation from the toxic effects of ammonia.

In the stomach and small intestine of a person there are no enzymes that would decompose lactulose for its absorption, therefore the active component of Dufalac reaches the large intestine unchanged. A small amount of the drug is absorbed. Metabolites are mainly excreted through the kidneys.

What is the drug prescribed for?

Constipation is manifested by a violation of the act of defecation. Bowel movements occur once every 2-3 days or less. The causes of constipation can be different: there is a violation of peristalsis, natural mechanisms do not work that normally regulate the change in food masses, their passage through the gastrointestinal tract.

The main indications for taking syrup with lactulose are episodic or chronic constipation, rare stools, and violations of the physiological rhythm of defecation.

Duphalac helps timely bowel movements and eliminates abdominal discomfort. Often, constipation is accompanied by pain, a feeling of tension below the waist. The drug is prescribed for hemorrhoids to soften the stool, reduce pain in the area of the nodes. You can also drink Duphalac before colon surgery.

Gastroenterologists recommend taking lactulose for dysbacteriosis and inflammation in the intestines. The remedy works better with an imbalance of the microbiota that has arisen against the background of the growth of a colony of Salmonella and Shigella. Syrup is given to children for food poisoning, putrefactive dyspepsia.

Dufalac is used as part of the complex treatment of obstructive jaundice, cirrhosis of the liver. The action of lactulose is useful in preventing the development of hepatic encephalopathy. Disaccharide inhibits the activity of microbes that release ammonia into the lumen of the colon during their life.

Lactulose prevents this poisonous gas from entering the bloodstream. Ammonium ions are formed, bound and removed from the body with the stool. After taking Dufalac, the concentration of ammonia in the intestine is almost halved. Less pronounced putrefactive dyspepsia.

How long does the remedy work?

The laxative effect does not occur immediately after taking Duphalac. How long lactulose acts on the colon depends on the nature of constipation, the duration of defecation disorders, body weight and age of the person. Therapeutic effect after the start of treatment with Dufalac, it may appear after 2 or 3 days.

Lactulose acts differently than laxatives, causing chemical irritation of the intestinal wall and increased peristalsis. Bisacodyl, candles with glycerin - drugs that help with constipation most quickly. Duphalac is a mild laxative.

Instructions for use Dufalac for children and adults

The syrup can be drunk undiluted, swallowed in one gulp, so that the solution does not linger in the mouth and throat, but enters the intestines faster. Before taking the remedy, you can add a small amount of liquid. This option is best suited for newborns and infants.

Syrup Duphalac, 200, 500, 1000 ml

Dosing for constipation and for softening stools

You can drink syrup once a day or divide the daily dose indicated in the table into 2 times. Measure the required amount of laxative with a measuring cup. Take the remedy during meals.

Dufalac in disposable sachets 15 ml

Dosing the drug in a sachet is no different from using a laxative in vials. A teenager or adult can take 1-3 sachets of Duphalac on the first day. If you need to drink the maximum amount of funds, then divide by two times. In the morning, take the contents of one sachet with breakfast, two more in the evening with dinner. After 2 days, you can switch to maintenance treatment (1-2 sachets / day). Schoolchildren aged 7-14 are enough to drink 15 ml / day, which corresponds to one sachet.

During pregnancy and lactation

Due to the low absorption of lactulose, the systemic effect of Duphalac is manifested to a small extent. The tool does not have a direct or indirect effect on the development of the fetus, does not penetrate into women's milk, and therefore does not affect the body of an infant. Duphalac during pregnancy, during lactation can be used without fear.

drug interaction

The decomposition of lactulose is accompanied by an increase in the acidity of the intestinal contents. A more acidic environment affects drugs whose release is pH dependent. 5-aminosalicylic acid preparations, such as Sulfasalazine and Mesalazine, may not show their activity. Means are used to treat inflammatory processes in the intestines, rheumatic diseases. The release of drugs occurs in the colon at certain acidity values.

Contraindications, side effects and overdose

Duphalac is not taken with intolerance to lactulose and its constituents. Contraindications for treatment are lactase enzyme deficiency, galactosemia, gastrointestinal perforation, intestinal obstruction.

Reception of Dufalac is rarely accompanied by side effects. There may be nausea, flatulence, allergic reactions, pain - abdominal, headache. Exceeding the dose is accompanied by diarrhea. The dangerous consequences of diarrhea are dehydration and electrolyte imbalance.

Dufalac's analogs

In Russia, Lactusan syrup is produced, containing lactulose. Indications for treatment with a remedy are constipation, intestinal dysbacteriosis and about 10 more serious health disorders, including liver disease. The cost of a bottle of syrup is 145 rubles (100 g).

Complete structural analogues of Dufalac are Normaze preparations (produced in Italy), Portalak (Croatia). The content of lactulose in syrups is the same - 667 mg / ml. If you want to determine which is better - Normaze or Dufalac, then the scales may tilt in favor of any of the drugs. Composition, indications and contraindications coincide almost completely.

Normase is recommended to be taken after meals. It is possible to treat constipation and dysbacteriosis in patients from birth. Dosages are indicated for the use of the drug in hepatic coma and encephalopathy. You should drink 30-60 ml of syrup after three main meals. Course - 3 months and longer. The price of a bottle of Normaze syrup is 285 rubles (200 ml).

Duphalac and structural analogues of laxatives are used for gentle bowel cleansing. The dose is determined based on the calculation of 1 ml of syrup per 1 kg of body weight. With a weight of 60 kg, 60 ml should be taken, dividing this amount of the drug into two times.

Lactulose is produced in the form of tablets. The name of the Russian remedy is Poslabin Lactulose. Price - 125 rubles (30 tablets).

An incomplete analogue of Duphalac is Dinolac emulsion. The combined preparation contains lactulose and defoamer simethicone. Due to the combination of drugs, Dinolac is not accompanied by bloating.

Dufalac's analogue according to the mechanism of action - Exportal. The cost of the drug is quite high for the products of domestic pharmaceutical concerns (520 rubles). Esportal contains whey products. Lactitol and lactulose are altered by intestinal bacteria, metabolites have an osmotic effect. Water and other reaction products are released, softening and increasing the volume of the stool.

If there is any doubt when choosing an analogue, it is better to contact the doctors. The doctor will select the most effective laxative.